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rhil 37  (R&D Systems)


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    R&D Systems rhil 37
    Rhil 37, supplied by R&D Systems, used in various techniques. Bioz Stars score: 93/100, based on 7 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/rhil 37/product/R&D Systems
    Average 93 stars, based on 7 article reviews
    rhil 37 - by Bioz Stars, 2026-06
    93/100 stars

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    IL-37 expression and the administration of rhIL-37 in the challenge phase attenuates OVA-induced eosinophilic airway inflammation and airway hyper-reactivity (AHR). ( A ) Protocol for OVA-induced asthmatic airway inflammation and the time points of rhIL-37 intervention during the sensitization phase. ( B ) The differential cell counts in BALF (n=10 mice per group). Numbers of cells were counted in ten random 1000X oil lens fields. ( C ) Airway resistance to methacholine was measured at 24 hours after final OVA challenge by using Flexivent FX-Mouse AN modular and invasion system (n=10 mice per group). ( D ) Representative photomicrographs of lung sections stained with H&E. original magnification, 10x, 20x, 40x. Columns and error bars represented mean±SEM. n=10 per group. *p< 0.05, **p< 0.01, ***p<0.01. Similar results were obtained from three to five independent experiments.

    Journal: Aging (Albany NY)

    Article Title: Cytokine antibody array-based analysis of IL-37 treatment effects in asthma

    doi: 10.18632/aging.203515

    Figure Lengend Snippet: IL-37 expression and the administration of rhIL-37 in the challenge phase attenuates OVA-induced eosinophilic airway inflammation and airway hyper-reactivity (AHR). ( A ) Protocol for OVA-induced asthmatic airway inflammation and the time points of rhIL-37 intervention during the sensitization phase. ( B ) The differential cell counts in BALF (n=10 mice per group). Numbers of cells were counted in ten random 1000X oil lens fields. ( C ) Airway resistance to methacholine was measured at 24 hours after final OVA challenge by using Flexivent FX-Mouse AN modular and invasion system (n=10 mice per group). ( D ) Representative photomicrographs of lung sections stained with H&E. original magnification, 10x, 20x, 40x. Columns and error bars represented mean±SEM. n=10 per group. *p< 0.05, **p< 0.01, ***p<0.01. Similar results were obtained from three to five independent experiments.

    Article Snippet: The mice in OVA/IL-37 group were treated with rhIL-37 (R&D System, USA, 200ng/dose) or with PBS as control 24h before OVA administration.

    Techniques: Expressing, Staining

    Immunohistochemistry detection of IL-18Ra, IL-18Rb, SIGIRR in mice lung tissue from PBS, OVA/PBS, OVA/rhIL-37 group (n=10 mice per group). Representative photomicrographs of immunohistochemistry staining for IL-18Ra ( A ), IL-18Rb ( B ) and SIGIRR ( C ) in mice lung tissue from each group. ( D ) Quantitation of IL-18Ra, IL-18Rb, SIGIRR expression. IL-18Ra and SIGIRR expression in the lung tissue of the OVA/IL-37 group was significantly upregulated compared to the OVA/PBS group, while the difference of IL-18Rb expression in the lung tissue of the OVA/IL-37 group was not statistically significant upregulated compared to the OVA/PBS group. Columns and error bars represented mean±SEM. n=10 per group. **p< 0.01, ***p<0.001. ****p<0.0001.

    Journal: Aging (Albany NY)

    Article Title: Cytokine antibody array-based analysis of IL-37 treatment effects in asthma

    doi: 10.18632/aging.203515

    Figure Lengend Snippet: Immunohistochemistry detection of IL-18Ra, IL-18Rb, SIGIRR in mice lung tissue from PBS, OVA/PBS, OVA/rhIL-37 group (n=10 mice per group). Representative photomicrographs of immunohistochemistry staining for IL-18Ra ( A ), IL-18Rb ( B ) and SIGIRR ( C ) in mice lung tissue from each group. ( D ) Quantitation of IL-18Ra, IL-18Rb, SIGIRR expression. IL-18Ra and SIGIRR expression in the lung tissue of the OVA/IL-37 group was significantly upregulated compared to the OVA/PBS group, while the difference of IL-18Rb expression in the lung tissue of the OVA/IL-37 group was not statistically significant upregulated compared to the OVA/PBS group. Columns and error bars represented mean±SEM. n=10 per group. **p< 0.01, ***p<0.001. ****p<0.0001.

    Article Snippet: The mice in OVA/IL-37 group were treated with rhIL-37 (R&D System, USA, 200ng/dose) or with PBS as control 24h before OVA administration.

    Techniques: Immunohistochemistry, Staining, Quantitation Assay, Expressing